CJC-1295 NO DAC
- Dosage
- 99% Purity
- 5mg
$54.00
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Certificate of Analysis
Scientific Overview
CJC-1295 (No DAC), also known as Modified GRF(1-29) or Mod GRF, is a synthetic GHRH analog consisting of the first 29 amino acids of GHRH with four amino acid substitutions to improve metabolic stability. Without the DAC conjugation, it has a shorter half-life (~30 minutes) and produces pulsatile GH release patterns more similar to physiological secretion.
Chemical Makeup
Molecular Formula
C₁₅₂H₂₅₂N₄₄O₄₂
Molecular Weight
3367.00 g/mol
Other Names
Mod GRF(1-29), Modified GRF(1-29), Tetrasubstituted GRF(1-29)
Appearance
White to off-white lyophilized powder
Storage
Store refrigerated at 2–8°C. For extended storage, keep frozen at -20°C. Protect from light and moisture.
Research & Clinical Studies
Pulsatile GH Release Pattern
Unlike CJC-1295 DAC which produces sustained GH elevation, the non-DAC version produces acute GH pulses that better mimic natural pituitary secretion patterns. This makes it preferred in research examining physiological GH release dynamics.
Amino Acid Substitutions for Stability
Four amino acid substitutions at positions 2, 8, 15, and 27 protect the peptide from enzymatic degradation by DPP-IV and other proteases, extending its half-life from ~7 minutes (native GRF) to approximately 30 minutes without altering receptor specificity.
References
- 1. Thorner, M.O. et al. "Growth hormone-releasing hormone and growth hormone-releasing peptide as therapeutic agents." Horm Res. 51(Suppl 3):64-7 (1999). View
- 2. Alba, M. et al. "Once-daily administration of CJC-1295, a long-acting GHRH analog, in normal elderly subjects." J Clin Endocrinol Metab. 91(10):3996-4003 (2006). View
Frequently Asked Questions
What is the purity of CJC-1295 NO DAC?
Our CJC-1295 NO DAC is verified at 98.5% purity through independent third-party HPLC analysis. Each production batch undergoes rigorous quality testing, and a Certificate of Analysis (COA) is available for review in our COA Library.
How should I store this peptide?
Store refrigerated at 2–8°C. For extended storage, keep frozen at -20°C. Protect from light and moisture. Once reconstituted, solutions should be used promptly or stored frozen to maintain stability. Avoid repeated freeze-thaw cycles for best results.
Do you provide Certificates of Analysis?
Yes — every batch we produce is independently tested via HPLC and mass spectrometry to confirm identity and purity. COAs for all current batches are publicly accessible through our COA Library.
How is the product shipped?
All orders ship within 24 hours of purchase via USPS Priority Mail. Products are carefully sealed and packaged to ensure stability during transit. Orders over $150 qualify for free shipping. If you receive a damaged, defective, or incorrect product, please contact our support team with photos within 48 hours of delivery.
Is this product for human consumption?
No. This product is sold exclusively for in-vitro laboratory and research purposes. It is not intended for human or animal consumption, nor for any diagnostic or therapeutic applications. Purchasers must be 18 years of age or older and assume full responsibility for lawful handling.